The iSCAN from illumina is a 'BeadChip' based platform (infinium) and as such very different from other array technologies. It has numerous advantages over other high-density microarrays, including:
1) 50-mer probe sequences for better selectivity and sensitivity;
2) greater than 30-fold feature redundancy for higher confidence fluorescent intensities;
3) high feature density allowing smaller reagent and sample volumes;
4) standardized hybridization set-ups for reproducible data generation across several types of data;
5) several data types produced on the same system/same technique allows for improved data integration.
A) Genekspression.
B) Single Nucleotide Polymorphisms (SNPs).
C) Copy number variation (CNV).
D) DNA methylation.