Oslo universitetssykehus HF 993 467 049 Postboks 4950 Nydalen Oslo 0424 Trine Kjellsen +47 91667242 trikje@ous-hf.no www.ous-hf.no 75148 E2018 KRE Institute for Cancer Research, Hybridisation-based Technology 75148 The Institute for core physiology, Institute for cancer research, Oslo University Hospital. Shall procure a system with hybridising-based technology (Nanostring). An understanding of genome dynamics, function and structure are decisive in order to improve our understanding of the biological mechanisms in health and diseases, which in turn gives more precise medicines. The core facility has lead the establishment and development of high genome flow gene technologies in Norway, which has given high quality and effect research and contributed to the competitiveness of research groups at OUH. As a part of our services, we would like to implement a platform that is compatible with FFPE material and low entrance material that enable direct and enzyme-free recognition and quantification of individual DNA and RNA molecules. The technology must be able to analyse gene expression, recognise fusion genes, as well as simple nucleotide variants and DNA copy number changes in hundreds of genes simultaneously. 2500000.00 Oslo University Hospital. The Institute for core physiology, Institute for cancer research, Oslo University Hospital. Shall procure a system with hybridising-based technology (Nanostring). An understanding of genome dynamics, function and structure are decisive in order to improve our understanding of the biological mechanisms in health and diseases, which in turn gives more precise medicines. The core facility has lead the establishment and development of high genome flow gene technologies in Norway, which has given high quality and effect research and contributed to the competitiveness of research groups at OUH. As a part of our services, we would like to implement a platform that is compatible with FFPE material and low entrance material that enable direct and enzyme-free recognition and quantification of individual DNA and RNA molecules. The technology must be able to analyse gene expression, recognise fusion genes, as well as simple nucleotide variants and DNA copy number changes in hundreds of genes simultaneously. A Requirements: — the system must use a new digital barcode technology that is based on direct hybridisation of the probe set without using cDNA synthesis and without amplification, — the system must be able to analyse up to 800 measurements simultaneously in one individual sample, — the system must carry out hybridisation of barcodes. Probes allow direct counting by the use of a simple molecule picture in order to give precise and sensitive quantification, — at the same time the technology must add measurements of gene expression of mRNA, microRNA, determine copy number changes, protein levels and gene fusions, amongst other applications. Conclusion: NCounter Sprint Profiles from Nanostring is a unique system that uses a new digital barcode technology that is based on direct hybridisation of the probe set without using cDNA synthesis and without amplification. The system is able to analyse up to 800 measurements simultaneously in one individual sample. The hybridisation of barcode probes allow direct counting by using a simple molecule picture in order to give precise and sensitive quantification. This technology can be used for simultaneous measurements of gene expression of mRNAs, microRNA, determining copy number changes, protein levels and gene fusions, amongst other applications. Nanostring is the only supplier of this type of technology. This is based on Nanostring Technologies Inc being the only supplier that, due to technical reasons, can deliver in accordance with the requirements. This is based on Nanostring Technologies Inc being the only supplier that, due to technical reasons, can deliver in accordance with the requirements. The intention notice is announced in accordance with the public procurement regulations §21-5. The terms in the public procurement regulations §13-4 (2) and 13-1 (5) are deemed to be fulfilled as well as the value of the full service contract for the equipment´s lifetime. The terms in the public procurement regulations § 13-4 (2) and 13-1 (5) are deemed to be fulfilled as well as the value of the full service contract for the equipment´s lifetime. The Institute for core physiology, Institute for cancer research, Oslo University Hospital. Shall procure a system with hybridisation-based technology (Nanostring). An understanding of genome dynamics, function and structure are decisive in order to improve our understanding of the biological mechanisms in health and diseases, which in turn gives more precise medicines. The core facility has lead the establishment and development of high genome flow gene technologies in Norway, which has given high quality and effect research and contributed to the competitiveness of research groups at OUH. As a part of our services, we would like to implement a platform that is compatible with FFPE material and low entrance material that enable direct and enzyme-free recognition and quantification of individual DNA and RNA molecules. The technology must be able to analyse gene expression, recognise fusion genes, as well as simple nucleotide variants and DNA copy number changes in hundreds of genes simultaneously. The system must use a new digital barcode technology that is based on direct hybridisation of the probe set without using cDNA synthesis and without amplification. The system must be able to analyse up to 800 measurements simultaneously in an individual sample. The system must carry out hybridisation of barcodes. Probes allow direct counting by the use of a simple molecule picture in order to give precise and sensitive quantification. At the same time the technology must add measurements of gene expression of mRNA, microRNA, determine copy number changes, protein levels and gene fusions, amongst other applications. NCounter Sprint Profiles from Nanostring is a unique system that uses a new digital barcode technology that is based on direct hybridisation of the probe set without using cDNA synthesis and without amplification. The system is able to analyse up to 800 measurements simultaneously in one individual sample. The hybridisation of barcode probes allow direct counting by using a simple molecule picture in order to give precise and sensitive quantification. This technology can be used for simultaneous measurements of gene expression of mRNAs, microRNA, determining copy number changes, protein levels and gene fusions, amongst other applications. Nanostring is the only supplier of this type of technology. This is based on Nanostring Technologies Inc being the only supplier that, due to technical reasons, can deliver in accordance with the requirements. The intention notice is announced in accordance with the public procurement regulations §21-5. The terms in the public procurement regulations §13-4 (2) and 31-1 (5) are deemed to be fulfilled as well as the value of the full service contract for the equipment´s lifetime. 75148 75148 E2018 KRE Institute for Cancer Research, hybridisation-based technology 2018-06-06 Nanostring Technologies 0001401708 530 Fairview Avenue N Seattle WA 98109 +001 8883586266 www.nanostring.com 2500000.00 Oslo Universitetssykehus HF Sognvannsveien 20 Oslo 0372 +47 23071580 mtu-anbud@ous-hf.no WWW.ous-hf.no Appeals deadline: 20.6.18. 2018-06-06
See tender at TED: http://ted.europa.eu/udl?uri=TED:NOTICE:247288-2018:TEXT:EN:HTML