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Confocal microscopy resolution limit is very close to the size of most intracellular organelles. Super-resolution applications allow us to resolve the intracellular distribution of proteins of interest within intracellular organelles by increasing our resolution power. Elyra PS1 features structured illumination microscopy (SIM) and PhotoActivation Localization Microscopy (PALM), which will fill in the gap between light and electron microscopy.